🧬 基因注释：DDX18
📝 官方信息
官方名称：DEAD-box helicase 18
功能摘要：DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it is activated by Myc protein. [provided by RefSeq, Jul 2008].
🎯 作为靶基因的剪接因子
- RBFOX2 综合评分: 0.522 · 证据 2 条
- FUS 综合评分: 0.424 · 证据 1 条
- fus 综合评分: 0.424 · 证据 1 条
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- HNRNPC 综合评分: 0.412 · 证据 2 条
- HNRNPK 综合评分: 0.398 · 证据 2 条
- HNRNPL 综合评分: 0.362 · 证据 2 条
- PTBP1 综合评分: 0.362 · 证据 2 条
- HNRNPM 综合评分: 0.350 · 证据 2 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- ELAVL3 综合评分: 0.329 · 证据 1 条
- PRPF8 综合评分: 0.324 · 证据 1 条
- Tardbp 综合评分: 0.324 · 证据 1 条
- RBM10 综合评分: 0.312 · 证据 2 条
- TIA1 综合评分: 0.312 · 证据 1 条
- HNRNPD 综合评分: 0.300 · 证据 2 条
- HNRNPU 综合评分: 0.300 · 证据 2 条
- KHSRP 综合评分: 0.300 · 证据 2 条
- SRSF2 综合评分: 0.300 · 证据 1 条
- SRSF3 综合评分: 0.300 · 证据 1 条
🏥 关联疾病
alcohol drinking
低关联 (0.312)
benign digestive system neoplasm
低关联 (0.273)
smoking initiation
低关联 (0.216)
Alzheimer disease
低关联 (0.196)
diabetes mellitus
低关联 (0.192)
congenital anomaly of cardiovascular system
低关联 (0.182)
physical activity
低关联 (0.181)
frozen shoulder
低关联 (0.177)
influenza A (H1N1)
低关联 (0.174)
injury
低关联 (0.173)