SpliceAtlasDB
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🧬 基因注释:DDX5

📝 官方信息

官方名称:DEAD-box helicase 5

功能摘要:This gene encodes a member of the DEAD box family of RNA helicases that are involved in a variety of cellular processes as a result of its role as an adaptor molecule, promoting interactions with a large number of other factors. This protein is involved in pathways that include the alteration of RNA structures, plays a role as a coregulator of transcription, a regulator of splicing, and in the processing of small noncoding RNAs. Members of this family contain nine conserved motifs, including the conserved Asp-Glu-Ala-Asp (DEAD) motif, important to ATP binding and hydrolysis as well as RNA binding and unwinding activities. Dysregulation of this gene may play a role in cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2017].

🎯 作为靶基因的剪接因子
  • HNRNPC 综合评分: 0.524 · 证据 2 条
  • FUS 综合评分: 0.460 · 证据 1 条
  • fus 综合评分: 0.460 · 证据 1 条
  • HNRNPA1 综合评分: 0.412 · 证据 2 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • SRSF9 综合评分: 0.398 · 证据 1 条
  • TIA1 综合评分: 0.394 · 证据 1 条
  • HNRNPK 综合评分: 0.362 · 证据 2 条
  • KHSRP 综合评分: 0.362 · 证据 2 条
  • SRSF2 综合评分: 0.362 · 证据 1 条
  • HNRNPH1 综合评分: 0.350 · 证据 2 条
  • HNRNPM 综合评分: 0.350 · 证据 2 条
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • FUBP1 综合评分: 0.348 · 证据 2 条
  • ELAVL3 综合评分: 0.342 · 证据 1 条
  • Nova2 综合评分: 0.324 · 证据 1 条
  • RBM10 综合评分: 0.312 · 证据 2 条
  • RBM15 综合评分: 0.312 · 证据 2 条
  • RBM22 综合评分: 0.312 · 证据 2 条
  • Tardbp 综合评分: 0.310 · 证据 1 条
🏥 关联疾病
COVID-19
低关联 (0.373)
colon adenocarcinoma
低关联 (0.371)
severe acute respiratory syndrome
低关联 (0.370)
colorectal adenocarcinoma
低关联 (0.370)
gliomatosis cerebri
低关联 (0.370)
dengue disease
低关联 (0.370)
hemangioblastoma
低关联 (0.370)
Endometrial Endometrioid Adenocarcinoma
低关联 (0.370)
skin squamous cell carcinoma
低关联 (0.370)
hepatocellular carcinoma
低关联 (0.304)
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