🧬 基因注释：DHX34
📝 官方信息
官方名称：DExH-box helicase 34
功能摘要：DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. It is mapped to the glioma 19q tumor suppressor region and is a tumor suppressor candidate gene. [provided by RefSeq, Jul 2008].
🎯 作为靶基因的剪接因子
- HNRNPC 综合评分: 0.494 · 证据 2 条
- HNRNPA2B1 综合评分: 0.474 · 证据 2 条
- HNRNPH1 综合评分: 0.474 · 证据 2 条
- Tardbp 综合评分: 0.465 · 证据 1 条
- SRSF2 综合评分: 0.444 · 证据 1 条
- HNRNPA1 综合评分: 0.412 · 证据 2 条
- HNRNPK 综合评分: 0.362 · 证据 2 条
- RBM15 综合评分: 0.312 · 证据 2 条
- FUS 综合评分: 0.300 · 证据 1 条
- PTBP1 综合评分: 0.300 · 证据 2 条
- RBFOX2 综合评分: 0.300 · 证据 2 条
- SRSF3 综合评分: 0.300 · 证据 1 条
- SRSF9 综合评分: 0.300 · 证据 1 条
- Srsf3 综合评分: 0.300 · 证据 1 条
- fus 综合评分: 0.300 · 证据 1 条
- PCBP2 综合评分: 0.262 · 证据 1 条
- EWSR1 综合评分: 0.250 · 证据 2 条
- RBM10 综合评分: 0.250 · 证据 2 条
- TIA1 综合评分: 0.250 · 证据 1 条
- Srsf1 综合评分: 0.248 · 证据 1 条
🏥 关联疾病
Neurodevelopmental disorder
中关联 (0.450)
neurodegenerative disease
低关联 (0.370)
Intellectual disability
低关联 (0.353)
Neurodevelopmental delay
低关联 (0.352)
Seizure
低关联 (0.301)
preeclampsia
低关联 (0.289)
osteitis deformans
低关联 (0.265)
Short stature
低关联 (0.259)
postaxial polydactyly
低关联 (0.259)
emphysema
低关联 (0.259)