基因注释 - DHX38

📝 官方信息

官方名称：DEAH-box helicase 38

功能摘要：DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a member of the DEAD/H box family of splicing factors. This protein resembles yeast Prp16 more closely than other DEAD/H family members. It is an ATPase and essential for the catalytic step II in pre-mRNA splicing process. [provided by RefSeq, Jul 2008].

🎯 作为靶基因的剪接因子

HNRNPM 综合评分: 0.474 · 证据 2 条
HNRNPC 综合评分: 0.448 · 证据 2 条
HNRNPA2B1 综合评分: 0.412 · 证据 2 条
SRSF2 综合评分: 0.362 · 证据 1 条
MBNL1 综合评分: 0.350 · 证据 2 条
RBM10 综合评分: 0.312 · 证据 2 条
FUS 综合评分: 0.300 · 证据 1 条
KHSRP 综合评分: 0.300 · 证据 2 条
PTBP1 综合评分: 0.300 · 证据 2 条
RBFOX2 综合评分: 0.300 · 证据 2 条
SRSF3 综合评分: 0.300 · 证据 1 条
SRSF9 综合评分: 0.300 · 证据 1 条
Srsf2 综合评分: 0.300 · 证据 1 条
Srsf3 综合评分: 0.300 · 证据 1 条
fus 综合评分: 0.300 · 证据 1 条
EWSR1 综合评分: 0.250 · 证据 2 条
RBM15 综合评分: 0.250 · 证据 2 条
RBM39 综合评分: 0.250 · 证据 2 条
TIA1 综合评分: 0.250 · 证据 1 条
Srsf1 综合评分: 0.248 · 证据 1 条

🏥 关联疾病

retinitis pigmentosa

中关联 (0.612)

neurodegenerative disease

中关联 (0.499)

Retinal dystrophy

低关联 (0.393)

retinitis pigmentosa 84

低关联 (0.375)

dengue disease

低关联 (0.370)

hyperlipidemia

低关联 (0.344)

coronary artery disease

低关联 (0.330)

Hypercholesterolemia

低关联 (0.310)

familial hyperlipidemia

低关联 (0.275)

ovarian neoplasm

低关联 (0.261)

🔍 查看该基因的所有关联疾病

🔗 外部数据库链接

NCBI Gene GenBank Ensembl GeneCards UniProt

🧬 基因注释：DHX38