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🧬 基因注释:DPP10

📝 官方信息

官方名称:dipeptidyl peptidase like 10

功能摘要:This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

🎯 作为靶基因的剪接因子
  • HNRNPC 综合评分: 0.350 · 证据 2 条
  • HNRNPM 综合评分: 0.350 · 证据 2 条
  • FUS 综合评分: 0.300 · 证据 1 条
  • HNRNPL 综合评分: 0.300 · 证据 2 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
  • RBFOX2 综合评分: 0.300 · 证据 2 条
  • fus 综合评分: 0.300 · 证据 1 条
  • Nova2 综合评分: 0.262 · 证据 1 条
  • Rbmx 综合评分: 0.260 · 证据 1 条
  • Rnps1 综合评分: 0.260 · 证据 1 条
  • EWSR1 综合评分: 0.250 · 证据 2 条
  • RBM10 综合评分: 0.250 · 证据 2 条
  • ACIN1 综合评分: 0.212 · 证据 2 条
  • CELF2 综合评分: 0.212 · 证据 2 条
  • CPSF6 综合评分: 0.212 · 证据 2 条
  • MBNL2 综合评分: 0.200 · 证据 1 条
  • Mbnl2 综合评分: 0.200 · 证据 1 条
  • NOVA1 综合评分: 0.200 · 证据 2 条
  • Ptbp2 综合评分: 0.200 · 证据 1 条
  • CPSF1 综合评分: 0.162 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

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