🧬 基因注释：DYNLL1

官方名称：dynein light chain LC8-type 1

功能摘要：Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008].

• FUS 综合评分: 0.496 · 证据 1 条
• fus 综合评分: 0.496 · 证据 1 条
• HNRNPC 综合评分: 0.448 · 证据 2 条
• RBFOX2 综合评分: 0.398 · 证据 2 条
• HNRNPL 综合评分: 0.362 · 证据 2 条
• ELAVL3 综合评分: 0.358 · 证据 1 条
• HNRNPA2B1 综合评分: 0.350 · 证据 2 条
• HNRNPH1 综合评分: 0.350 · 证据 2 条
• EWSR1 综合评分: 0.312 · 证据 2 条
• RBM15 综合评分: 0.312 · 证据 2 条
• TIA1 综合评分: 0.312 · 证据 1 条
• HNRNPU 综合评分: 0.300 · 证据 2 条
• PTBP1 综合评分: 0.300 · 证据 2 条
• SRSF3 综合评分: 0.300 · 证据 1 条
• SRSF9 综合评分: 0.300 · 证据 1 条
• Srsf3 综合评分: 0.300 · 证据 1 条
• Ptbp2 综合评分: 0.298 · 证据 1 条
• PRPF8 综合评分: 0.262 · 证据 1 条
• RBM39 综合评分: 0.250 · 证据 2 条
• Srsf2 综合评分: 0.248 · 证据 1 条

该基因暂无关联疾病记录