🧬 基因注释：DYNLT1
官方名称：dynein light chain Tctex-type 1
功能摘要：This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014].
- HNRNPC 综合评分: 0.494 · 证据 2 条
- FUS 综合评分: 0.486 · 证据 1 条
- fus 综合评分: 0.486 · 证据 1 条
- Tardbp 综合评分: 0.448 · 证据 1 条
- PTBP1 综合评分: 0.444 · 证据 2 条
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- RBFOX2 综合评分: 0.362 · 证据 2 条
- U2af1 综合评分: 0.310 · 证据 1 条
- HNRNPU 综合评分: 0.300 · 证据 2 条
- SRSF3 综合评分: 0.300 · 证据 1 条
- PRPF8 综合评分: 0.298 · 证据 1 条
- Rbmx 综合评分: 0.274 · 证据 1 条
- U2af2 综合评分: 0.274 · 证据 1 条
- UPF1 综合评分: 0.274 · 证据 1 条
- EWSR1 综合评分: 0.250 · 证据 2 条
- RBM10 综合评分: 0.250 · 证据 2 条
- RBM15 综合评分: 0.250 · 证据 2 条
- TIA1 综合评分: 0.250 · 证据 1 条
- GRSF1 综合评分: 0.248 · 证据 2 条
- Srsf1 综合评分: 0.248 · 证据 1 条
该基因暂无关联疾病记录