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🧬 基因注释:DNAJB5

📝 官方信息

官方名称:DnaJ heat shock protein family (Hsp40) member B5

功能摘要:This gene encodes a member of the DNAJ heat shock protein 40 family of co-chaperone proteins. The encoded protein contains an N-terminal DNAJ domain and a C-terminal substrate binding domain but lacks the cysteine-rich domain found in other DNAJ family members. In mice, a multi-protein complex containing this protein, thioredoxin 1, and histone deacetylase 4, serves as a master negative regulator of cardiac hypertrophy. [provided by RefSeq, Mar 2017].

🎯 作为靶基因的剪接因子
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • Nova2 综合评分: 0.324 · 证据 1 条
  • Mbnl2 综合评分: 0.298 · 证据 1 条
  • RBM15 综合评分: 0.250 · 证据 2 条
  • NOVA1 综合评分: 0.200 · 证据 2 条
  • Rbpms 综合评分: 0.162 · 证据 1 条
  • U2af1 综合评分: 0.150 · 证据 1 条
  • Rnps1 综合评分: 0.100 · 证据 1 条
  • Srsf7 综合评分: 0.100 · 证据 1 条
  • YBX1 综合评分: 0.100 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

🔗 外部数据库链接