🧬 基因注释：DUSP1
📝 官方信息
官方名称：dual specificity phosphatase 1
功能摘要：The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy. [provided by RefSeq, Aug 2017].
🎯 作为靶基因的剪接因子
- Srsf3 综合评分: 0.424 · 证据 1 条
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- HNRNPC 综合评分: 0.350 · 证据 2 条
- Rnps1 综合评分: 0.348 · 证据 1 条
- Tardbp 综合评分: 0.346 · 证据 1 条
- Nova2 综合评分: 0.324 · 证据 1 条
- EWSR1 综合评分: 0.312 · 证据 2 条
- PTBP1 综合评分: 0.300 · 证据 2 条
- SRSF3 综合评分: 0.300 · 证据 1 条
- SRSF9 综合评分: 0.300 · 证据 1 条
- UPF1 综合评分: 0.286 · 证据 1 条
- ACIN1 综合评分: 0.274 · 证据 2 条
- ELAVL3 综合评分: 0.274 · 证据 1 条
- U2af2 综合评分: 0.274 · 证据 1 条
- PCBP2 综合评分: 0.262 · 证据 1 条
- PRPF8 综合评分: 0.262 · 证据 1 条
- RBM15 综合评分: 0.250 · 证据 2 条
- Srsf1 综合评分: 0.212 · 证据 1 条
- Rbmx 综合评分: 0.198 · 证据 1 条
- NXF1 综合评分: 0.162 · 证据 1 条
🏥 关联疾病
该基因暂无关联疾病记录