🧬 基因注释：EDARADD

官方名称：EDAR associated via death domain

功能摘要：This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

• HNRNPA2B1 综合评分: 0.412 · 证据 2 条
• PTBP1 综合评分: 0.362 · 证据 2 条
• HNRNPC 综合评分: 0.350 · 证据 2 条
• HNRNPM 综合评分: 0.350 · 证据 2 条
• MBNL1 综合评分: 0.350 · 证据 2 条
• EWSR1 综合评分: 0.312 · 证据 2 条
• FUS 综合评分: 0.300 · 证据 1 条
• SRSF9 综合评分: 0.300 · 证据 1 条
• fus 综合评分: 0.300 · 证据 1 条
• PRPF8 综合评分: 0.262 · 证据 1 条
• RBM10 综合评分: 0.250 · 证据 2 条
• RBM15 综合评分: 0.250 · 证据 2 条
• YBX1 综合评分: 0.224 · 证据 1 条
• ACIN1 综合评分: 0.212 · 证据 2 条
• CPSF6 综合评分: 0.212 · 证据 2 条
• SF3A3 综合评分: 0.200 · 证据 1 条
• RBM20 综合评分: 0.198 · 证据 2 条
• Tra2b 综合评分: 0.198 · 证据 1 条
• EIF4A3 综合评分: 0.162 · 证据 2 条
• U2af2 综合评分: 0.162 · 证据 1 条

该基因暂无关联疾病记录