🧬 基因注释:ELAVL1
📝 官方信息
官方名称:ELAV like RNA binding protein 1
功能摘要:The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012].
🎯 作为靶基因的剪接因子
- HNRNPC 综合评分: 0.510 · 证据 2 条
- HNRNPH1 综合评分: 0.448 · 证据 2 条
- FUS 综合评分: 0.398 · 证据 1 条
- HNRNPK 综合评分: 0.398 · 证据 2 条
- fus 综合评分: 0.398 · 证据 1 条
- KHSRP 综合评分: 0.362 · 证据 2 条
- HNRNPA2B1 综合评分: 0.350 · 证据 2 条
- HNRNPM 综合评分: 0.350 · 证据 2 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- QKI 综合评分: 0.350 · 证据 1 条
- PRPF8 综合评分: 0.324 · 证据 1 条
- ELAVL3 综合评分: 0.322 · 证据 1 条
- UPF1 综合评分: 0.314 · 证据 1 条
- RBM15 综合评分: 0.312 · 证据 2 条
- TIA1 综合评分: 0.312 · 证据 1 条
- HNRNPU 综合评分: 0.300 · 证据 2 条
- PTBP1 综合评分: 0.300 · 证据 2 条
- RBFOX2 综合评分: 0.300 · 证据 2 条
- SRSF2 综合评分: 0.300 · 证据 1 条
- SRSF3 综合评分: 0.300 · 证据 1 条
🏥 关联疾病
neurodegenerative disease
中关联 (0.457)
dengue disease
低关联 (0.371)
nervous system disease
低关联 (0.200)
bone remodeling disease
低关联 (0.198)
Cerebral degeneration
低关联 (0.153)
Abnormal nasolacrimal system morphology
低关联 (0.124)
sinusitis
低关联 (0.123)
neoplasm
低关联 (0.118)
cancer
低关联 (0.113)
hepatocellular carcinoma
低关联 (0.111)