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🧬 基因注释:ELAVL2

📝 官方信息

官方名称:ELAV like RNA binding protein 2

功能摘要:In humans, the ELAV like RNA binding protein gene family has four members (ELAVL1-4). ELAVL RNA binding proteins recognize AU-rich elements in the 3' UTRs of gene transcripts and thereby regulate gene expression post-transcriptionally. The protein encoded by this gene binds to several 3' UTRs, including its own and also that of FOS, ID, and POU5F1. This gene encodes ELAVL2 and, like ELAVL3 and ELAVL4, is expressed specifically in neurons and primarily localizes to the cytoplasm. This protein also forms a cytosolic complex with the normally nuclear-localized ELAVL1 protein. Alternative splicing of this gene results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Jul 2020].

🎯 作为靶基因的剪接因子
  • HNRNPA2B1 综合评分: 0.350 · 证据 2 条
  • HNRNPC 综合评分: 0.350 · 证据 2 条
  • HNRNPM 综合评分: 0.350 · 证据 2 条
  • QKI 综合评分: 0.350 · 证据 1 条
  • MBNL2 综合评分: 0.344 · 证据 1 条
  • ELAVL3 综合评分: 0.342 · 证据 1 条
  • EWSR1 综合评分: 0.312 · 证据 2 条
  • FUS 综合评分: 0.300 · 证据 1 条
  • KHSRP 综合评分: 0.300 · 证据 2 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
  • RBFOX2 综合评分: 0.300 · 证据 2 条
  • fus 综合评分: 0.300 · 证据 1 条
  • Mbnl2 综合评分: 0.262 · 证据 1 条
  • FUBP1 综合评分: 0.250 · 证据 2 条
  • RBM10 综合评分: 0.250 · 证据 2 条
  • RBM15 综合评分: 0.250 · 证据 2 条
  • TIA1 综合评分: 0.250 · 证据 1 条
  • CPSF6 综合评分: 0.212 · 证据 2 条
  • Tardbp 综合评分: 0.212 · 证据 1 条
  • Nova2 综合评分: 0.200 · 证据 1 条
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major depressive disorder
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chronic obstructive pulmonary disease
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mathematical ability
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低关联 (0.390)
substance-related disorder
低关联 (0.380)
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