🧬 基因注释：EPHB4

官方名称：EPH receptor B4

功能摘要：Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. [provided by RefSeq, Jul 2008].

• FUS 综合评分: 0.362 · 证据 1 条
• RBFOX2 综合评分: 0.362 · 证据 2 条
• fus 综合评分: 0.362 · 证据 1 条
• PCBP2 综合评分: 0.360 · 证据 1 条
• HNRNPA2B1 综合评分: 0.350 · 证据 2 条
• HNRNPC 综合评分: 0.350 · 证据 2 条
• HNRNPH1 综合评分: 0.350 · 证据 2 条
• MBNL1 综合评分: 0.350 · 证据 2 条
• TIA1 综合评分: 0.312 · 证据 1 条
• HNRNPK 综合评分: 0.300 · 证据 2 条
• PTBP1 综合评分: 0.300 · 证据 2 条
• SRSF9 综合评分: 0.300 · 证据 1 条
• CSTF2 综合评分: 0.274 · 证据 2 条
• RBM15 综合评分: 0.250 · 证据 2 条
• Srsf3 综合评分: 0.248 · 证据 1 条
• U2af2 综合评分: 0.244 · 证据 1 条
• UPF1 综合评分: 0.244 · 证据 1 条
• YBX1 综合评分: 0.244 · 证据 1 条
• Rnps1 综合评分: 0.224 · 证据 1 条
• AQR 综合评分: 0.212 · 证据 1 条

该基因暂无关联疾病记录