🧬 基因注释：EIF2AK4
📝 官方信息
官方名称：eukaryotic translation initiation factor 2 alpha kinase 4
功能摘要：This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014].
🎯 作为靶基因的剪接因子
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- HNRNPC 综合评分: 0.412 · 证据 2 条
- FUS 综合评分: 0.398 · 证据 1 条
- HNRNPK 综合评分: 0.398 · 证据 2 条
- fus 综合评分: 0.398 · 证据 1 条
- Tardbp 综合评分: 0.398 · 证据 1 条
- RBFOX2 综合评分: 0.362 · 证据 2 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- NOVA1 综合评分: 0.324 · 证据 2 条
- HNRNPL 综合评分: 0.300 · 证据 2 条
- HNRNPU 综合评分: 0.300 · 证据 2 条
- KHSRP 综合评分: 0.300 · 证据 2 条
- PTBP1 综合评分: 0.300 · 证据 2 条
- CSTF2 综合评分: 0.274 · 证据 2 条
- PCBP2 综合评分: 0.262 · 证据 1 条
- RBM10 综合评分: 0.250 · 证据 2 条
- RBM15 综合评分: 0.250 · 证据 2 条
- TIA1 综合评分: 0.250 · 证据 1 条
- Mbnl2 综合评分: 0.200 · 证据 1 条
- Nova2 综合评分: 0.200 · 证据 1 条
🏥 关联疾病
该基因暂无关联疾病记录