🧬 基因注释：ENO1
📝 官方信息
官方名称：enolase 1
功能摘要：This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. [provided by RefSeq, Jan 2011].
🎯 作为靶基因的剪接因子
- HNRNPC 综合评分: 0.613 · 证据 2 条
- RBFOX2 综合评分: 0.496 · 证据 2 条
- FUS 综合评分: 0.474 · 证据 1 条
- HNRNPA2B1 综合评分: 0.474 · 证据 2 条
- fus 综合评分: 0.474 · 证据 1 条
- Srsf3 综合评分: 0.444 · 证据 1 条
- HNRNPK 综合评分: 0.398 · 证据 2 条
- PTBP1 综合评分: 0.362 · 证据 2 条
- MBNL2 综合评分: 0.360 · 证据 1 条
- U2af1 综合评分: 0.356 · 证据 1 条
- HNRNPA1 综合评分: 0.350 · 证据 2 条
- HNRNPH1 综合评分: 0.350 · 证据 2 条
- HNRNPM 综合评分: 0.350 · 证据 2 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- QKI 综合评分: 0.350 · 证据 1 条
- CELF2 综合评分: 0.324 · 证据 2 条
- PCBP2 综合评分: 0.324 · 证据 1 条
- Rnps1 综合评分: 0.322 · 证据 1 条
- EWSR1 综合评分: 0.312 · 证据 2 条
- RBM10 综合评分: 0.312 · 证据 2 条
🏥 关联疾病
该基因暂无关联疾病记录