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🧬 基因注释:F11R

📝 官方信息

官方名称:F11 receptor

功能摘要:Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008].

🎯 作为靶基因的剪接因子
  • HNRNPM 综合评分: 0.448 · 证据 2 条
  • Tardbp 综合评分: 0.403 · 证据 1 条
  • HNRNPK 综合评分: 0.398 · 证据 2 条
  • PTBP1 综合评分: 0.362 · 证据 2 条
  • HNRNPA1 综合评分: 0.350 · 证据 2 条
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • FUS 综合评分: 0.300 · 证据 1 条
  • HNRNPU 综合评分: 0.300 · 证据 2 条
  • RBFOX2 综合评分: 0.300 · 证据 2 条
  • SRSF3 综合评分: 0.300 · 证据 1 条
  • Srsf3 综合评分: 0.300 · 证据 1 条
  • fus 综合评分: 0.300 · 证据 1 条
  • PCBP2 综合评分: 0.262 · 证据 1 条
  • RBM15 综合评分: 0.250 · 证据 2 条
  • TIA1 综合评分: 0.250 · 证据 1 条
  • CSTF2 综合评分: 0.248 · 证据 2 条
  • AQR 综合评分: 0.212 · 证据 1 条
  • CPSF7 综合评分: 0.212 · 证据 2 条
  • GRSF1 综合评分: 0.212 · 证据 2 条
  • PCBP1 综合评分: 0.200 · 证据 2 条
🏥 关联疾病

该基因暂无关联疾病记录

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