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基因注释:FMO2

官方信息

官方名称:flavin containing dimethylaniline monoxygenase 2

功能摘要:This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014].

作为靶基因的剪接因子
  • SRSF9 综合评分: 0.300 · 证据 1 条
  • Srsf7 综合评分: 0.100 · 证据 1 条
关联疾病

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