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🧬 基因注释:FN1

📝 官方信息

官方名称:fibronectin 1

功能摘要:This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined. [provided by RefSeq, Jan 2016].

🎯 作为靶基因的剪接因子
  • SRSF1 综合评分: 0.579 · 证据 1 条
  • Srsf1 综合评分: 0.579 · 证据 1 条
  • FUS 综合评分: 0.460 · 证据 1 条
  • fus 综合评分: 0.460 · 证据 1 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • RBFOX2 综合评分: 0.398 · 证据 2 条
  • HNRNPK 综合评分: 0.362 · 证据 2 条
  • HNRNPU 综合评分: 0.362 · 证据 2 条
  • HNRNPA1 综合评分: 0.350 · 证据 2 条
  • HNRNPC 综合评分: 0.350 · 证据 2 条
  • HNRNPM 综合评分: 0.350 · 证据 2 条
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • QKI 综合评分: 0.350 · 证据 1 条
  • SRSF11 综合评分: 0.307 · 证据 1 条
  • SRSF4 综合评分: 0.307 · 证据 1 条
  • Srsf4 综合评分: 0.307 · 证据 2 条
  • HNRNPL 综合评分: 0.300 · 证据 2 条
  • KHSRP 综合评分: 0.300 · 证据 2 条
  • SRSF10 综合评分: 0.300 · 证据 1 条
  • SRSF3 综合评分: 0.300 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

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