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🧬 基因注释:FBXO3

📝 官方信息

官方名称:F-box protein 3

功能摘要:This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants diverging at the 3' end. [provided by RefSeq, Jul 2008].

🎯 作为靶基因的剪接因子
  • HNRNPC 综合评分: 0.510 · 证据 2 条
  • RBFOX2 综合评分: 0.460 · 证据 2 条
  • HNRNPH1 综合评分: 0.412 · 证据 2 条
  • HNRNPM 综合评分: 0.412 · 证据 2 条
  • PTBP1 综合评分: 0.398 · 证据 2 条
  • HNRNPA2B1 综合评分: 0.350 · 证据 2 条
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • QKI 综合评分: 0.350 · 证据 1 条
  • Nova2 综合评分: 0.344 · 证据 1 条
  • Tardbp 综合评分: 0.324 · 证据 1 条
  • FUBP1 综合评分: 0.312 · 证据 2 条
  • RBM10 综合评分: 0.312 · 证据 2 条
  • FUS 综合评分: 0.300 · 证据 1 条
  • HNRNPL 综合评分: 0.300 · 证据 2 条
  • fus 综合评分: 0.300 · 证据 1 条
  • ELAVL3 综合评分: 0.274 · 证据 1 条
  • Mbnl2 综合评分: 0.262 · 证据 1 条
  • Ptbp2 综合评分: 0.262 · 证据 1 条
  • RBM15 综合评分: 0.250 · 证据 2 条
  • Srsf1 综合评分: 0.212 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

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