🧬 基因注释：FTH1
📝 官方信息
官方名称：ferritin heavy chain 1
功能摘要：This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
🎯 作为靶基因的剪接因子
- RBFOX2 综合评分: 0.522 · 证据 2 条
- HNRNPC 综合评分: 0.494 · 证据 2 条
- FUS 综合评分: 0.486 · 证据 1 条
- fus 综合评分: 0.486 · 证据 1 条
- Srsf3 综合评分: 0.424 · 证据 1 条
- Tardbp 综合评分: 0.422 · 证据 1 条
- HNRNPA1 综合评分: 0.412 · 证据 2 条
- HNRNPL 综合评分: 0.398 · 证据 2 条
- Nova2 综合评分: 0.374 · 证据 1 条
- HNRNPK 综合评分: 0.362 · 证据 2 条
- PTBP1 综合评分: 0.362 · 证据 2 条
- SRSF9 综合评分: 0.362 · 证据 1 条
- HNRNPA2B1 综合评分: 0.350 · 证据 2 条
- HNRNPM 综合评分: 0.350 · 证据 2 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- QKI 综合评分: 0.350 · 证据 1 条
- EWSR1 综合评分: 0.348 · 证据 2 条
- RBM39 综合评分: 0.348 · 证据 2 条
- ELAVL3 综合评分: 0.336 · 证据 1 条
- Rnps1 综合评分: 0.329 · 证据 1 条
🏥 关联疾病
该基因暂无关联疾病记录