🧬 基因注释：G6PD

官方名称：glucose-6-phosphate dehydrogenase

功能摘要：This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

• HNRNPC 综合评分: 0.412 · 证据 2 条
• HNRNPK 综合评分: 0.398 · 证据 2 条
• Tardbp 综合评分: 0.356 · 证据 1 条
• MBNL1 综合评分: 0.350 · 证据 2 条
• PCBP2 综合评分: 0.324 · 证据 1 条
• TIA1 综合评分: 0.312 · 证据 1 条
• PTBP1 综合评分: 0.300 · 证据 2 条
• RBFOX2 综合评分: 0.300 · 证据 2 条
• SRSF3 综合评分: 0.300 · 证据 1 条
• YBX1 综合评分: 0.260 · 证据 1 条
• RBM10 综合评分: 0.250 · 证据 2 条
• RBM15 综合评分: 0.250 · 证据 2 条
• RBM39 综合评分: 0.250 · 证据 2 条
• UPF1 综合评分: 0.244 · 证据 1 条
• Srsf1 综合评分: 0.212 · 证据 1 条
• PRPF8 综合评分: 0.200 · 证据 1 条
• SF3A3 综合评分: 0.200 · 证据 1 条
• EIF4A3 综合评分: 0.198 · 证据 2 条
• Rbmx 综合评分: 0.198 · 证据 1 条
• Rnps1 综合评分: 0.162 · 证据 1 条

该基因暂无关联疾病记录