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基因注释:GAL3ST2

官方信息

官方名称:galactose-3-O-sulfotransferase 2

功能摘要:This gene encodes a member of the galactose-3-O-sulfotransferase protein family. The product of this gene catalyzes sulfonation by transferring a sulfate group to the hydroxyl at C-3 of nonreducing beta-galactosyl residues, and it can act on both type 1 and type 2 (Galbeta 1-3/1-4GlcNAc-R) oligosaccharides with similar efficiencies, and on core 1 glycans. This enzyme has been implicated in tumor metastasis processes. This gene is different from the GAL3ST3 gene located on chromosome 11, which has also been referred to as GAL3ST2 and encodes a related enzyme with distinct tissue distribution and substrate specificities, compared to galactose-3-O-sulfotransferase 2. [provided by RefSeq, Jul 2008].

作为靶基因的剪接因子
  • HNRNPC 综合评分: 0.350 · 证据 2 条
  • RBM15 综合评分: 0.250 · 证据 2 条
  • PRPF8 综合评分: 0.200 · 证据 1 条
  • CSTF2T 综合评分: 0.162 · 证据 2 条
  • U2af1 综合评分: 0.150 · 证据 1 条
  • CPSF1 综合评分: 0.100 · 证据 1 条
  • NXF1 综合评分: 0.100 · 证据 1 条
  • Rbmx 综合评分: 0.100 · 证据 1 条
关联疾病

该基因暂无关联疾病记录

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