🧬 基因注释：GCSH

官方名称：glycine cleavage system protein H

功能摘要：Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.[provided by RefSeq, Jan 2010].

• HNRNPC 综合评分: 0.494 · 证据 2 条
• RBFOX2 综合评分: 0.474 · 证据 2 条
• HNRNPA2B1 综合评分: 0.350 · 证据 2 条
• FUS 综合评分: 0.300 · 证据 1 条
• HNRNPU 综合评分: 0.300 · 证据 2 条
• PTBP1 综合评分: 0.300 · 证据 2 条
• fus 综合评分: 0.300 · 证据 1 条
• CSTF2 综合评分: 0.274 · 证据 2 条
• Tardbp 综合评分: 0.274 · 证据 1 条
• U2af2 综合评分: 0.260 · 证据 1 条
• EWSR1 综合评分: 0.250 · 证据 2 条
• RBM15 综合评分: 0.250 · 证据 2 条
• TIA1 综合评分: 0.250 · 证据 1 条
• UPF1 综合评分: 0.224 · 证据 1 条
• AQR 综合评分: 0.212 · 证据 1 条
• PRPF8 综合评分: 0.200 · 证据 1 条
• CSTF2T 综合评分: 0.162 · 证据 2 条
• NXF1 综合评分: 0.162 · 证据 1 条
• MSI1 综合评分: 0.150 · 证据 1 条
• Srsf4 综合评分: 0.150 · 证据 1 条

该基因暂无关联疾病记录