🧬 基因注释：GLUL
官方名称：glutamate-ammonia ligase
功能摘要：The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014].
- HNRNPC 综合评分: 0.556 · 证据 2 条
- FUS 综合评分: 0.529 · 证据 1 条
- fus 综合评分: 0.529 · 证据 1 条
- RBFOX2 综合评分: 0.514 · 证据 2 条
- Tardbp 综合评分: 0.438 · 证据 1 条
- HNRNPK 综合评分: 0.424 · 证据 2 条
- SRSF2 综合评分: 0.424 · 证据 1 条
- HNRNPH1 综合评分: 0.412 · 证据 2 条
- PTBP1 综合评分: 0.398 · 证据 2 条
- ELAVL3 综合评分: 0.380 · 证据 1 条
- Srsf3 综合评分: 0.362 · 证据 1 条
- HNRNPA1 综合评分: 0.350 · 证据 2 条
- HNRNPA2B1 综合评分: 0.350 · 证据 2 条
- HNRNPM 综合评分: 0.350 · 证据 2 条
- QKI 综合评分: 0.350 · 证据 1 条
- TIA1 综合评分: 0.348 · 证据 1 条
- U2af1 综合评分: 0.336 · 证据 1 条
- PCBP2 综合评分: 0.324 · 证据 1 条
- RBM10 综合评分: 0.312 · 证据 2 条
- RBM22 综合评分: 0.312 · 证据 2 条
该基因暂无关联疾病记录