🧬 基因注释：GADD45B

官方名称：growth arrest and DNA damage inducible beta

功能摘要：This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. [provided by RefSeq, Jul 2008].

• RBFOX2 综合评分: 0.444 · 证据 2 条
• HNRNPK 综合评分: 0.424 · 证据 2 条
• SRSF9 综合评分: 0.362 · 证据 1 条
• HNRNPA2B1 综合评分: 0.350 · 证据 2 条
• MBNL1 综合评分: 0.350 · 证据 2 条
• RBM15 综合评分: 0.312 · 证据 2 条
• PTBP1 综合评分: 0.300 · 证据 2 条
• Srsf3 综合评分: 0.274 · 证据 1 条
• PRPF8 综合评分: 0.262 · 证据 1 条
• RBM39 综合评分: 0.250 · 证据 2 条
• TIA1 综合评分: 0.250 · 证据 1 条
• Srsf1 综合评分: 0.248 · 证据 1 条
• Tardbp 综合评分: 0.248 · 证据 1 条
• Rbm7 综合评分: 0.198 · 证据 1 条
• YBX1 综合评分: 0.198 · 证据 1 条
• UPF1 综合评分: 0.162 · 证据 1 条
• ACIN1 综合评分: 0.150 · 证据 2 条
• AQR 综合评分: 0.150 · 证据 1 条
• CPSF6 综合评分: 0.150 · 证据 2 条
• CPSF7 综合评分: 0.150 · 证据 2 条

该基因暂无关联疾病记录