基因注释：GLI1
官方信息
官方名称：GLI family zinc finger 1
功能摘要：This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009].
作为靶基因的剪接因子
关联疾病
该基因暂无关联疾病记录