SpliceAtlasDB
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🧬 基因注释:H1-3

📝 官方信息

官方名称:H1.3 linker histone, cluster member

功能摘要:Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015].

🎯 作为靶基因的剪接因子
  • RBFOX2 综合评分: 0.474 · 证据 2 条
  • Tardbp 综合评分: 0.364 · 证据 1 条
  • TIA1 综合评分: 0.312 · 证据 1 条
  • FUS 综合评分: 0.300 · 证据 1 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
  • fus 综合评分: 0.300 · 证据 1 条
  • RBM15 综合评分: 0.250 · 证据 2 条
  • RBM39 综合评分: 0.250 · 证据 2 条
  • CPSF6 综合评分: 0.212 · 证据 2 条
  • DDX5 综合评分: 0.212 · 证据 2 条
  • U2af1 综合评分: 0.212 · 证据 1 条
  • NXF1 综合评分: 0.162 · 证据 1 条
  • CPSF7 综合评分: 0.150 · 证据 2 条
  • PABPC4 综合评分: 0.150 · 证据 2 条
  • CSTF2T 综合评分: 0.100 · 证据 2 条
  • Rbmx 综合评分: 0.100 · 证据 1 条
  • U2af2 综合评分: 0.100 · 证据 1 条
  • UPF1 综合评分: 0.100 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

🔗 外部数据库链接