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🧬 基因注释:H2AC17

📝 官方信息

官方名称:H2A clustered histone 17

功能摘要:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015].

🎯 作为靶基因的剪接因子
  • FUS 综合评分: 0.496 · 证据 1 条
  • fus 综合评分: 0.496 · 证据 1 条
  • HNRNPC 综合评分: 0.474 · 证据 2 条
  • RBFOX2 综合评分: 0.474 · 证据 2 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • TIA1 综合评分: 0.348 · 证据 1 条
  • EWSR1 综合评分: 0.312 · 证据 2 条
  • RBM15 综合评分: 0.312 · 证据 2 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
  • SRSF2 综合评分: 0.300 · 证据 1 条
  • SRSF9 综合评分: 0.300 · 证据 1 条
  • PCBP2 综合评分: 0.298 · 证据 1 条
  • ACIN1 综合评分: 0.294 · 证据 2 条
  • UPF1 综合评分: 0.244 · 证据 1 条
  • YBX1 综合评分: 0.224 · 证据 1 条
  • CPSF6 综合评分: 0.212 · 证据 2 条
  • TFIP11 综合评分: 0.212 · 证据 1 条
  • Rbm7 综合评分: 0.198 · 证据 1 条
  • EIF4A3 综合评分: 0.162 · 证据 2 条
🏥 关联疾病

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