🧬 基因注释：H2AX
📝 官方信息
官方名称：H2A.X variant histone
功能摘要：Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015].
🎯 作为靶基因的剪接因子
- HNRNPC 综合评分: 0.510 · 证据 2 条
- FUS 综合评分: 0.496 · 证据 1 条
- fus 综合评分: 0.496 · 证据 1 条
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- Tardbp 综合评分: 0.403 · 证据 1 条
- HNRNPM 综合评分: 0.350 · 证据 2 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- TIA1 综合评分: 0.348 · 证据 1 条
- RBM15 综合评分: 0.312 · 证据 2 条
- HNRNPK 综合评分: 0.300 · 证据 2 条
- KHSRP 综合评分: 0.300 · 证据 2 条
- RBFOX2 综合评分: 0.300 · 证据 2 条
- SRSF9 综合评分: 0.300 · 证据 1 条
- PCBP1 综合评分: 0.298 · 证据 2 条
- PCBP2 综合评分: 0.298 · 证据 1 条
- Rbmx 综合评分: 0.296 · 证据 1 条
- UPF1 综合评分: 0.296 · 证据 1 条
- U2af1 综合评分: 0.294 · 证据 1 条
- PRPF8 综合评分: 0.262 · 证据 1 条
- EWSR1 综合评分: 0.250 · 证据 2 条
🏥 关联疾病
该基因暂无关联疾病记录