🧬 基因注释：H2AZ1

官方名称：H2A.Z variant histone 1

功能摘要：Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008].

• FUS 综合评分: 0.529 · 证据 1 条
• fus 综合评分: 0.529 · 证据 1 条
• HNRNPC 综合评分: 0.510 · 证据 2 条
• Tardbp 综合评分: 0.498 · 证据 1 条
• RBFOX2 综合评分: 0.486 · 证据 2 条
• Srsf3 综合评分: 0.460 · 证据 1 条
• HNRNPH1 综合评分: 0.448 · 证据 2 条
• HNRNPA2B1 综合评分: 0.412 · 证据 2 条
• HNRNPM 综合评分: 0.412 · 证据 2 条
• PTBP1 综合评分: 0.398 · 证据 2 条
• Srsf2 综合评分: 0.398 · 证据 1 条
• EWSR1 综合评分: 0.374 · 证据 2 条
• SRSF9 综合评分: 0.362 · 证据 1 条
• MBNL1 综合评分: 0.350 · 证据 2 条
• CELF2 综合评分: 0.324 · 证据 2 条
• PCBP2 综合评分: 0.324 · 证据 1 条
• RBM10 综合评分: 0.312 · 证据 2 条
• HNRNPL 综合评分: 0.300 · 证据 2 条
• KHSRP 综合评分: 0.300 · 证据 2 条
• SRSF2 综合评分: 0.300 · 证据 1 条

该基因暂无关联疾病记录