🧬 基因注释：H2BC8
官方名称：H2B clustered histone 8
功能摘要：Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein has antibacterial and antifungal antimicrobial activity. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015].
- ACIN1 置信度: 2.0
- CSTF2 置信度: 2.0
- CSTF2T 置信度: 2.0
- EIF4A3 置信度: 2.0
- EWSR1 置信度: 2.0
- HNRNPC 置信度: 2.0
- PTBP1 置信度: 2.0
- RBM39 置信度: 2.0
- ELAVL3 置信度: 1.0
- FUS 置信度: 1.0
- LUC7L2 置信度: 1.0
- Larp7 置信度: 1.0
- PCBP2 置信度: 1.0
- Rbm7 置信度: 1.0
- Rnps1 置信度: 1.0
- SRSF2 置信度: 1.0
- Srsf1 置信度: 1.0
- Srsf2 置信度: 1.0
- Srsf3 置信度: 1.0
- Srsf4 置信度: 1.0
该基因暂无关联疾病记录