🧬 基因注释：H2BC8

官方名称：H2B clustered histone 8

功能摘要：Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein has antibacterial and antifungal antimicrobial activity. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015].

• FUS 综合评分: 0.496 · 证据 1 条
• fus 综合评分: 0.496 · 证据 1 条
• Srsf2 综合评分: 0.362 · 证据 1 条
• HNRNPC 综合评分: 0.350 · 证据 2 条
• U2af1 综合评分: 0.336 · 证据 1 条
• EWSR1 综合评分: 0.312 · 证据 2 条
• Srsf3 综合评分: 0.310 · 证据 1 条
• PTBP1 综合评分: 0.300 · 证据 2 条
• SRSF2 综合评分: 0.300 · 证据 1 条
• CSTF2 综合评分: 0.274 · 证据 2 条
• PCBP2 综合评分: 0.262 · 证据 1 条
• RBM39 综合评分: 0.250 · 证据 2 条
• TIA1 综合评分: 0.250 · 证据 1 条
• ACIN1 综合评分: 0.248 · 证据 2 条
• Srsf1 综合评分: 0.248 · 证据 1 条
• Tardbp 综合评分: 0.248 · 证据 1 条
• Tra2a 综合评分: 0.224 · 证据 1 条
• UPF1 综合评分: 0.224 · 证据 1 条
• Srsf4 综合评分: 0.212 · 证据 1 条
• EIF4A3 综合评分: 0.162 · 证据 2 条

该基因暂无关联疾病记录