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🧬 基因注释:H3-5

📝 官方信息

官方名称:H3.5 histone

功能摘要:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded by this gene is a replication-independent histone that is a member of the histone H3 family. [provided by RefSeq, Oct 2015].

🎯 作为靶基因的剪接因子
  • Tardbp 综合评分: 0.480 · 证据 1 条
  • FUS 综合评分: 0.474 · 证据 1 条
  • fus 综合评分: 0.474 · 证据 1 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • KHSRP 综合评分: 0.362 · 证据 2 条
  • RBFOX2 综合评分: 0.362 · 证据 2 条
  • HNRNPC 综合评分: 0.350 · 证据 2 条
  • TIA1 综合评分: 0.312 · 证据 1 条
  • HNRNPU 综合评分: 0.300 · 证据 2 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
  • SRSF2 综合评分: 0.300 · 证据 1 条
  • MBNL2 综合评分: 0.298 · 证据 1 条
  • CPSF6 综合评分: 0.274 · 证据 2 条
  • GRSF1 综合评分: 0.274 · 证据 2 条
  • Rnps1 综合评分: 0.274 · 证据 1 条
  • EWSR1 综合评分: 0.250 · 证据 2 条
  • FUBP1 综合评分: 0.250 · 证据 2 条
  • RBM15 综合评分: 0.250 · 证据 2 条
  • Srsf1 综合评分: 0.248 · 证据 1 条
  • PABPC4 综合评分: 0.212 · 证据 2 条
🏥 关联疾病

该基因暂无关联疾病记录

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