SpliceAtlasDB
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🧬 基因注释:H4C11

📝 官方信息

官方名称:H4 clustered histone 11

功能摘要:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015].

🎯 作为靶基因的剪接因子
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • Srsf2 综合评分: 0.362 · 证据 1 条
  • EWSR1 综合评分: 0.312 · 证据 2 条
  • Srsf3 综合评分: 0.310 · 证据 1 条
  • Rnps1 综合评分: 0.306 · 证据 1 条
  • HNRNPL 综合评分: 0.300 · 证据 2 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
  • SRSF2 综合评分: 0.300 · 证据 1 条
  • ACIN1 综合评分: 0.294 · 证据 2 条
  • PCBP2 综合评分: 0.262 · 证据 1 条
  • Srsf4 综合评分: 0.248 · 证据 1 条
  • U2af2 综合评分: 0.224 · 证据 1 条
  • CPSF6 综合评分: 0.212 · 证据 2 条
  • Srsf7 综合评分: 0.162 · 证据 1 条
  • CELF2 综合评分: 0.150 · 证据 2 条
  • CPSF4 综合评分: 0.150 · 证据 2 条
  • Srsf1 综合评分: 0.150 · 证据 1 条
  • Tardbp 综合评分: 0.150 · 证据 1 条
  • CPSF3 综合评分: 0.100 · 证据 1 条
  • CSTF2T 综合评分: 0.100 · 证据 2 条
🏥 关联疾病

该基因暂无关联疾病记录

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