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🧬 基因注释:H4C14

📝 官方信息

官方名称:H4 clustered histone 14

功能摘要:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy. [provided by RefSeq, Aug 2015].

🎯 作为靶基因的剪接因子
  • FUS 综合评分: 0.506 · 证据 1 条
  • fus 综合评分: 0.506 · 证据 1 条
  • Tardbp 综合评分: 0.496 · 证据 1 条
  • HNRNPA2B1 综合评分: 0.448 · 证据 2 条
  • HNRNPC 综合评分: 0.448 · 证据 2 条
  • PTBP1 综合评分: 0.424 · 证据 2 条
  • HNRNPU 综合评分: 0.362 · 证据 2 条
  • SRSF2 综合评分: 0.362 · 证据 1 条
  • Srsf2 综合评分: 0.362 · 证据 1 条
  • HNRNPM 综合评分: 0.350 · 证据 2 条
  • EWSR1 综合评分: 0.348 · 证据 2 条
  • TIA1 综合评分: 0.348 · 证据 1 条
  • U2af1 综合评分: 0.346 · 证据 1 条
  • Rnps1 综合评分: 0.322 · 证据 1 条
  • RBM15 综合评分: 0.312 · 证据 2 条
  • ACIN1 综合评分: 0.310 · 证据 2 条
  • Srsf3 综合评分: 0.310 · 证据 1 条
  • PCBP2 综合评分: 0.298 · 证据 1 条
  • Rbmx 综合评分: 0.286 · 证据 1 条
  • GRSF1 综合评分: 0.274 · 证据 2 条
🏥 关联疾病

该基因暂无关联疾病记录

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