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🧬 基因注释:H4C15

📝 官方信息

官方名称:H4 clustered histone 15

功能摘要:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-dependent histone that is a member of the histone H4 family. Some transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy. [provided by RefSeq, May 2020].

🎯 作为靶基因的剪接因子
  • HNRNPC 综合评分: 0.510 · 证据 2 条
  • FUS 综合评分: 0.506 · 证据 1 条
  • fus 综合评分: 0.506 · 证据 1 条
  • RBFOX2 综合评分: 0.486 · 证据 2 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • SRSF2 综合评分: 0.362 · 证据 1 条
  • HNRNPA1 综合评分: 0.350 · 证据 2 条
  • HNRNPM 综合评分: 0.350 · 证据 2 条
  • TIA1 综合评分: 0.348 · 证据 1 条
  • ACIN1 综合评分: 0.310 · 证据 2 条
  • HNRNPL 综合评分: 0.300 · 证据 2 条
  • HNRNPU 综合评分: 0.300 · 证据 2 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
  • GRSF1 综合评分: 0.274 · 证据 2 条
  • EWSR1 综合评分: 0.250 · 证据 2 条
  • RBM15 综合评分: 0.250 · 证据 2 条
  • CPSF7 综合评分: 0.248 · 证据 2 条
  • CPSF1 综合评分: 0.224 · 证据 1 条
  • Tardbp 综合评分: 0.212 · 证据 1 条
  • PCBP2 综合评分: 0.200 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

🔗 外部数据库链接