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基因注释:HCK

官方信息

官方名称:HCK proto-oncogene, Src family tyrosine kinase

功能摘要:The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon. [provided by RefSeq, Feb 2010].

作为靶基因的剪接因子
  • NXF1 综合评分: 0.162 · 证据 1 条
  • U2af1 综合评分: 0.150 · 证据 1 条
  • RBM20 综合评分: 0.100 · 证据 2 条
  • Srsf7 综合评分: 0.100 · 证据 1 条
关联疾病

该基因暂无关联疾病记录

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