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基因注释:HEPN1

官方信息

官方名称:hepatocellular carcinoma, down-regulated 1

功能摘要:This gene is expressed predominantly in the liver. Transient transfection studies show the expression of this gene significantly inhibits cell growth, suggesting a role for this gene in apoptosis. Expression of this gene is down-regulated or lost in hepatocellular carcinomas (HCC), suggesting that loss of this gene is involved in carcinogenesis of hepatocytes (PMID:12971969). This gene maps to the 3'-noncoding region of the HEPACAM gene (GeneID:220296) on the antisense strand. [provided by RefSeq, Aug 2020].

作为靶基因的剪接因子
  • HNRNPC 综合评分: 0.350 · 证据 2 条
  • TIA1 综合评分: 0.250 · 证据 1 条
  • PCBP2 综合评分: 0.200 · 证据 1 条
  • U2af1 综合评分: 0.150 · 证据 1 条
关联疾病

该基因暂无关联疾病记录

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