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🧬 基因注释:HNRNPDL

📝 官方信息

官方名称:heterogeneous nuclear ribonucleoprotein D like

功能摘要:This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind to RNAs. Three alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein isoforms encoded by this gene are similar to its family member HNRPD. [provided by RefSeq, May 2011].

🎯 作为靶基因的剪接因子
  • HNRNPC 综合评分: 0.510 · 证据 2 条
  • FUS 综合评分: 0.506 · 证据 1 条
  • fus 综合评分: 0.506 · 证据 1 条
  • HNRNPH1 综合评分: 0.494 · 证据 2 条
  • SRSF2 综合评分: 0.424 · 证据 1 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • HNRNPM 综合评分: 0.412 · 证据 2 条
  • PTBP1 综合评分: 0.398 · 证据 2 条
  • Tardbp 综合评分: 0.398 · 证据 1 条
  • FUBP1 综合评分: 0.394 · 证据 2 条
  • HNRNPK 综合评分: 0.362 · 证据 2 条
  • KHSRP 综合评分: 0.362 · 证据 2 条
  • HNRNPA1 综合评分: 0.350 · 证据 2 条
  • HNRNPF 综合评分: 0.350 · 证据 2 条
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • QKI 综合评分: 0.350 · 证据 1 条
  • RBM10 综合评分: 0.312 · 证据 2 条
  • RBM22 综合评分: 0.312 · 证据 2 条
  • RBM39 综合评分: 0.312 · 证据 2 条
  • Srsf3 综合评分: 0.310 · 证据 1 条
🏥 关联疾病
autosomal dominant limb-girdle muscular dystrophy type 1G
中关联 (0.684)
limb-girdle muscular dystrophy
低关联 (0.372)
Autosomal dominant limb-girdle muscular dystrophy
低关联 (0.370)
muscular dystrophy, limb-girdle, autosomal dominant
低关联 (0.370)
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🔗 外部数据库链接