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🧬 基因注释:HNRNPH3

📝 官方信息

官方名称:heterogeneous nuclear ribonucleoprotein H3

功能摘要:This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes. Several alternatively spliced transcript variants have been noted for this gene, however, not all are fully characterized. [provided by RefSeq, Jul 2008].

🎯 作为靶基因的剪接因子
  • HNRNPC 综合评分: 0.510 · 证据 2 条
  • HNRNPH1 综合评分: 0.474 · 证据 2 条
  • HNRNPM 综合评分: 0.448 · 证据 2 条
  • FUS 综合评分: 0.444 · 证据 1 条
  • RBFOX2 综合评分: 0.444 · 证据 2 条
  • fus 综合评分: 0.444 · 证据 1 条
  • HNRNPA1 综合评分: 0.412 · 证据 2 条
  • HNRNPK 综合评分: 0.398 · 证据 2 条
  • HNRNPU 综合评分: 0.398 · 证据 2 条
  • KHSRP 综合评分: 0.362 · 证据 2 条
  • Srsf3 综合评分: 0.362 · 证据 1 条
  • HNRNPA2B1 综合评分: 0.350 · 证据 2 条
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • QKI 综合评分: 0.350 · 证据 1 条
  • FUBP1 综合评分: 0.348 · 证据 2 条
  • TIA1 综合评分: 0.348 · 证据 1 条
  • Srsf1 综合评分: 0.310 · 证据 1 条
  • Tardbp 综合评分: 0.310 · 证据 1 条
  • U2af1 综合评分: 0.310 · 证据 1 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
🏥 关联疾病

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