🧬 基因注释：HNRNPL
官方名称：heterogeneous nuclear ribonucleoprotein L
功能摘要：Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
- HNRNPC 综合评分: 0.579 · 证据 2 条
- HNRNPL 综合评分: 0.529 · 证据 2 条
- RBFOX2 综合评分: 0.486 · 证据 2 条
- HNRNPH1 综合评分: 0.474 · 证据 2 条
- PTBP1 综合评分: 0.460 · 证据 2 条
- TIA1 综合评分: 0.446 · 证据 1 条
- Tardbp 综合评分: 0.438 · 证据 1 条
- FUS 综合评分: 0.424 · 证据 1 条
- HNRNPK 综合评分: 0.424 · 证据 2 条
- SRSF2 综合评分: 0.424 · 证据 1 条
- fus 综合评分: 0.424 · 证据 1 条
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- Srsf3 综合评分: 0.398 · 证据 1 条
- U2af1 综合评分: 0.392 · 证据 1 条
- ELAVL3 综合评分: 0.363 · 证据 1 条
- KHSRP 综合评分: 0.362 · 证据 2 条
- Srsf2 综合评分: 0.362 · 证据 1 条
- HNRNPA1 综合评分: 0.350 · 证据 2 条
- HNRNPM 综合评分: 0.350 · 证据 2 条
- MBNL1 综合评分: 0.350 · 证据 2 条
该基因暂无关联疾病记录