🧬 基因注释：HOXD10
📝 官方信息
官方名称：homeobox D10
功能摘要：This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as 'rocker-bottom foot' deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008].
🎯 作为靶基因的剪接因子
- HNRNPC 综合评分: 0.448 · 证据 2 条
- HNRNPH1 综合评分: 0.448 · 证据 2 条
- FUS 综合评分: 0.398 · 证据 1 条
- fus 综合评分: 0.398 · 证据 1 条
- TIA1 综合评分: 0.374 · 证据 1 条
- HNRNPD 综合评分: 0.362 · 证据 2 条
- RBFOX2 综合评分: 0.362 · 证据 2 条
- QKI 综合评分: 0.350 · 证据 1 条
- RBM10 综合评分: 0.312 · 证据 2 条
- RBM15 综合评分: 0.312 · 证据 2 条
- KHSRP 综合评分: 0.300 · 证据 2 条
- PTBP1 综合评分: 0.300 · 证据 2 条
- SRSF9 综合评分: 0.300 · 证据 1 条
- Rbmx 综合评分: 0.286 · 证据 1 条
- EWSR1 综合评分: 0.250 · 证据 2 条
- CPSF7 综合评分: 0.248 · 证据 2 条
- Tardbp 综合评分: 0.248 · 证据 1 条
- CPSF6 综合评分: 0.212 · 证据 2 条
- GRSF1 综合评分: 0.212 · 证据 2 条
- Rbpms 综合评分: 0.162 · 证据 1 条
🏥 关联疾病
该基因暂无关联疾病记录