🧬 基因注释：HSPB1

官方名称：heat shock protein family B (small) member 1

功能摘要：This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. [provided by RefSeq, Aug 2017].

• HNRNPC 综合评分: 0.412 · 证据 2 条
• PTBP1 综合评分: 0.398 · 证据 2 条
• TIA1 综合评分: 0.374 · 证据 1 条
• FUS 综合评分: 0.362 · 证据 1 条
• HNRNPK 综合评分: 0.362 · 证据 2 条
• fus 综合评分: 0.362 · 证据 1 条
• HNRNPA2B1 综合评分: 0.350 · 证据 2 条
• MBNL1 综合评分: 0.350 · 证据 2 条
• QKI 综合评分: 0.350 · 证据 1 条
• HNRNPL 综合评分: 0.300 · 证据 2 条
• RBFOX2 综合评分: 0.300 · 证据 2 条
• CSTF2 综合评分: 0.274 · 证据 2 条
• PCBP1 综合评分: 0.262 · 证据 2 条
• Rnps1 综合评分: 0.260 · 证据 1 条
• Rbm7 综合评分: 0.224 · 证据 1 条
• UPF1 综合评分: 0.224 · 证据 1 条
• YBX1 综合评分: 0.224 · 证据 1 条
• Srsf1 综合评分: 0.212 · 证据 1 条
• Srsf3 综合评分: 0.212 · 证据 1 条
• Mbnl2 综合评分: 0.200 · 证据 1 条

该基因暂无关联疾病记录