🧬 基因注释：HTRA2
📝 官方信息
官方名称：HtrA serine peptidase 2
功能摘要：This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016].
🎯 作为靶基因的剪接因子
- RBFOX2 综合评分: 0.362 · 证据 2 条
- HNRNPA2B1 综合评分: 0.350 · 证据 2 条
- HNRNPH1 综合评分: 0.350 · 证据 2 条
- HNRNPM 综合评分: 0.350 · 证据 2 条
- PRPF8 综合评分: 0.324 · 证据 1 条
- EWSR1 综合评分: 0.312 · 证据 2 条
- FUS 综合评分: 0.300 · 证据 1 条
- PTBP1 综合评分: 0.300 · 证据 2 条
- fus 综合评分: 0.300 · 证据 1 条
- U2af2 综合评分: 0.260 · 证据 1 条
- UPF1 综合评分: 0.260 · 证据 1 条
- RBM10 综合评分: 0.250 · 证据 2 条
- RBM15 综合评分: 0.250 · 证据 2 条
- AQR 综合评分: 0.248 · 证据 1 条
- Tardbp 综合评分: 0.248 · 证据 1 条
- Rnps1 综合评分: 0.244 · 证据 1 条
- Srsf3 综合评分: 0.212 · 证据 1 条
- CPSF6 综合评分: 0.150 · 证据 2 条
- GRSF1 综合评分: 0.150 · 证据 2 条
- PRPF4 综合评分: 0.150 · 证据 1 条
🏥 关联疾病
该基因暂无关联疾病记录