🧬 基因注释：HYAL2

官方名称：hyaluronidase 2

功能摘要：This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.[provided by RefSeq, Mar 2010].

• FUS 综合评分: 0.362 · 证据 1 条
• Srsf3 综合评分: 0.362 · 证据 1 条
• fus 综合评分: 0.362 · 证据 1 条
• RBM15 综合评分: 0.312 · 证据 2 条
• RBFOX2 综合评分: 0.300 · 证据 2 条
• SRSF3 综合评分: 0.300 · 证据 1 条
• PCBP2 综合评分: 0.298 · 证据 1 条
• PRPF8 综合评分: 0.262 · 证据 1 条
• TIA1 综合评分: 0.250 · 证据 1 条
• Rbmx 综合评分: 0.224 · 证据 1 条
• U2af2 综合评分: 0.162 · 证据 1 条
• YBX1 综合评分: 0.162 · 证据 1 条
• AQR 综合评分: 0.150 · 证据 1 条
• MSI1 综合评分: 0.150 · 证据 1 条
• Srsf2 综合评分: 0.150 · 证据 1 条
• TFIP11 综合评分: 0.150 · 证据 1 条
• Tardbp 综合评分: 0.150 · 证据 1 条
• U2af1 综合评分: 0.150 · 证据 1 条
• EIF4A3 综合评分: 0.100 · 证据 2 条
• Rbm7 综合评分: 0.100 · 证据 1 条

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