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🧬 基因注释:HCFC1

📝 官方信息

官方名称:host cell factor C1

功能摘要:This gene is a member of the host cell factor family and encodes a protein with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N-terminal chain and the corresponding C-terminal chain. The final form of this protein consists of noncovalently bound N- and C-terminal chains. The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008].

🎯 作为靶基因的剪接因子
  • HNRNPC 综合评分: 0.546 · 证据 2 条
  • PTBP1 综合评分: 0.460 · 证据 2 条
  • RBFOX2 综合评分: 0.460 · 证据 2 条
  • FUS 综合评分: 0.444 · 证据 1 条
  • fus 综合评分: 0.444 · 证据 1 条
  • Srsf3 综合评分: 0.424 · 证据 1 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • HNRNPH1 综合评分: 0.412 · 证据 2 条
  • HNRNPM 综合评分: 0.412 · 证据 2 条
  • Srsf2 综合评分: 0.362 · 证据 1 条
  • PCBP2 综合评分: 0.360 · 证据 1 条
  • Tardbp 综合评分: 0.356 · 证据 1 条
  • HNRNPA1 综合评分: 0.350 · 证据 2 条
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • CELF2 综合评分: 0.324 · 证据 2 条
  • RBM15 综合评分: 0.312 · 证据 2 条
  • U2af2 综合评分: 0.306 · 证据 1 条
  • HNRNPK 综合评分: 0.300 · 证据 2 条
  • KHSRP 综合评分: 0.300 · 证据 2 条
  • SRSF2 综合评分: 0.300 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

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