🧬 基因注释:HSPA8
📝 官方信息
官方名称:heat shock protein family A (Hsp70) member 8
功能摘要:This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
🎯 作为靶基因的剪接因子
- HNRNPC 综合评分: 0.556 · 证据 2 条
- Tardbp 综合评分: 0.522 · 证据 1 条
- FUS 综合评分: 0.496 · 证据 1 条
- RBFOX2 综合评分: 0.496 · 证据 2 条
- fus 综合评分: 0.496 · 证据 1 条
- SRSF2 综合评分: 0.474 · 证据 1 条
- PTBP1 综合评分: 0.460 · 证据 2 条
- HNRNPF 综合评分: 0.448 · 证据 2 条
- Srsf3 综合评分: 0.424 · 证据 1 条
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- QKI 综合评分: 0.412 · 证据 1 条
- Srsf2 综合评分: 0.398 · 证据 1 条
- U2af1 综合评分: 0.379 · 证据 1 条
- HNRNPL 综合评分: 0.362 · 证据 2 条
- HNRNPU 综合评分: 0.362 · 证据 2 条
- KHSRP 综合评分: 0.362 · 证据 2 条
- CELF2 综合评分: 0.356 · 证据 2 条
- HNRNPA1 综合评分: 0.350 · 证据 2 条
- HNRNPH1 综合评分: 0.350 · 证据 2 条
- HNRNPM 综合评分: 0.350 · 证据 2 条
🏥 关联疾病
dengue disease
中关联 (0.505)
systemic lupus erythematosus
低关联 (0.374)
smoking initiation
低关联 (0.210)
adolescent idiopathic scoliosis
低关联 (0.124)
Lennox-Gastaut syndrome
低关联 (0.118)
hepatocellular carcinoma
低关联 (0.107)