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🧬 基因注释:ICAM5

📝 官方信息

官方名称:intercellular adhesion molecule 5

功能摘要:The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. [provided by RefSeq, Jul 2008].

🎯 作为靶基因的剪接因子
  • HNRNPK 综合评分: 0.444 · 证据 2 条
  • FUS 综合评分: 0.362 · 证据 1 条
  • PTBP1 综合评分: 0.362 · 证据 2 条
  • SRSF2 综合评分: 0.362 · 证据 1 条
  • fus 综合评分: 0.362 · 证据 1 条
  • HNRNPH1 综合评分: 0.350 · 证据 2 条
  • HNRNPM 综合评分: 0.350 · 证据 2 条
  • HNRNPU 综合评分: 0.300 · 证据 2 条
  • RBFOX2 综合评分: 0.300 · 证据 2 条
  • SRSF9 综合评分: 0.300 · 证据 1 条
  • RBM15 综合评分: 0.250 · 证据 2 条
  • RBM22 综合评分: 0.250 · 证据 2 条
  • U2af1 综合评分: 0.248 · 证据 1 条
  • PRPF4 综合评分: 0.212 · 证据 1 条
  • Srsf1 综合评分: 0.212 · 证据 1 条
  • PRPF8 综合评分: 0.200 · 证据 1 条
  • Rnps1 综合评分: 0.198 · 证据 1 条
  • U2af2 综合评分: 0.198 · 证据 1 条
  • CSTF2T 综合评分: 0.162 · 证据 2 条
  • NXF1 综合评分: 0.162 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

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