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🧬 基因注释:IL4I1

📝 官方信息

官方名称:interleukin 4 induced 1

功能摘要:This gene encodes a secreted L-amino acid oxidase protein which primarily catabolizes L-phenylalanine and, to a lesser extent, L-arginine. The expression of this gene is induced by the cytokine interleukin 4 in B cells. This gene is also expressed in macrophages and dendritic cells. This protein may play a role immune system escape as it is expressed in tumor-associated macrophages and suppresses T-cell responses. This protein also contains domains thought to be involved in the binding of flavin adenine dinucleotide (FAD) cofactor. Multiple transcript variants encoding different isoforms have been found for this gene. Some transcripts of this gene share a promoter and exons of the 5' UTR with the overlapping NUP62 gene. [provided by RefSeq, Jul 2020].

🎯 作为靶基因的剪接因子
  • HNRNPC 综合评分: 0.510 · 证据 2 条
  • FUS 综合评分: 0.474 · 证据 1 条
  • HNRNPM 综合评分: 0.474 · 证据 2 条
  • fus 综合评分: 0.474 · 证据 1 条
  • HNRNPH1 综合评分: 0.448 · 证据 2 条
  • Tardbp 综合评分: 0.364 · 证据 1 条
  • PTBP1 综合评分: 0.362 · 证据 2 条
  • SRSF2 综合评分: 0.362 · 证据 1 条
  • HNRNPA2B1 综合评分: 0.350 · 证据 2 条
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • EWSR1 综合评分: 0.312 · 证据 2 条
  • RBM15 综合评分: 0.312 · 证据 2 条
  • TIA1 综合评分: 0.312 · 证据 1 条
  • CELF2 综合评分: 0.310 · 证据 2 条
  • UPF1 综合评分: 0.306 · 证据 1 条
  • HNRNPK 综合评分: 0.300 · 证据 2 条
  • HNRNPL 综合评分: 0.300 · 证据 2 条
  • HNRNPU 综合评分: 0.300 · 证据 2 条
  • KHSRP 综合评分: 0.300 · 证据 2 条
  • RBFOX2 综合评分: 0.300 · 证据 2 条
🏥 关联疾病

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