🧬 基因注释：IL6R

官方名称：interleukin 6 receptor

功能摘要：This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been identified in this gene. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, Aug 2020].

• HNRNPK 综合评分: 0.362 · 证据 2 条
• RBFOX2 综合评分: 0.362 · 证据 2 条
• HNRNPM 综合评分: 0.350 · 证据 2 条
• RBM10 综合评分: 0.312 · 证据 2 条
• HNRNPL 综合评分: 0.300 · 证据 2 条
• HNRNPU 综合评分: 0.300 · 证据 2 条
• SRSF9 综合评分: 0.300 · 证据 1 条
• PRPF8 综合评分: 0.200 · 证据 1 条
• CSTF2 综合评分: 0.150 · 证据 2 条
• GRSF1 综合评分: 0.150 · 证据 2 条
• PRPF4 综合评分: 0.150 · 证据 1 条
• Srsf1 综合评分: 0.150 · 证据 1 条
• U2af1 综合评分: 0.150 · 证据 1 条
• CSTF2T 综合评分: 0.100 · 证据 2 条
• RBM20 综合评分: 0.100 · 证据 2 条
• Rnps1 综合评分: 0.100 · 证据 1 条
• Srsf7 综合评分: 0.100 · 证据 1 条
• U2af2 综合评分: 0.100 · 证据 1 条
• UPF1 综合评分: 0.100 · 证据 1 条

该基因暂无关联疾病记录