SpliceAtlasDB
← 返回基因注释查询

🧬 基因注释:INMT

📝 官方信息

官方名称:indolethylamine N-methyltransferase

功能摘要:N-methylation of endogenous and xenobiotic compounds is a major method by which they are degraded. This gene encodes an enzyme that N-methylates indoles such as tryptamine. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream MINDY4 (aka FAM188B) gene. In rodents and other mammals such as cetartiodactyla this gene is in the opposite orientation compared to its orientation in human and other primates and this gene appears to have been lost in carnivora and chiroptera. [provided by RefSeq, Jul 2019].

🎯 作为靶基因的剪接因子
  • HNRNPM 综合评分: 0.350 · 证据 2 条
  • RBFOX2 综合评分: 0.300 · 证据 2 条
  • Tardbp 综合评分: 0.248 · 证据 1 条
  • NOVA1 综合评分: 0.200 · 证据 2 条
  • CPSF4 综合评分: 0.150 · 证据 2 条
  • U2af1 综合评分: 0.150 · 证据 1 条
  • CPSF3 综合评分: 0.100 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

🔗 外部数据库链接